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Updated: NIH says SIGA’s antiviral didn’t improve resolution in mpox lesions...
A day after the World Health Organization again declared mpox a public health emergency, more bad news came out about the virus. On Thursday, the National Institutes of Health said that SIGA...
View ArticleMerck signs MoU with Indian CDMO; Scorpius delays public offering
Welcome to Endpoints News’ manufacturing briefs, where we bring you essential news on new builds, collaborations, recalls and more. Merck and Indian CDMO Aragen have signed a memorandum of...
View ArticleLyra pauses work on sinusitis drug; Pathos AI licenses a new asset
Plus, news about Convergent Therapeutics, Turnstone Biologics and Sonnet BioTherapeutics: Lyra Therapeutics pauses development of chronic rhinosinusitis drug: The company now plans to focus on two...
View ArticleBavarian Nordic returns to the spotlight as mpox outbreak reaches emergency...
Bavarian Nordic is capable of supplying around three million doses of its mpox vaccine Jynneos this year, the WHO said following its global health emergency declaration. WHO Director-General Tedros...
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Lykos cutting most of staff less than a week after FDA rejection
Lykos Therapeutics is cutting 75% of its staff following the FDA’s rejection last week of its MDMA-assisted therapy, the company said Thursday. Rick Doblin Rick Doblin, founder and president of the...
View ArticleMedicare price negotiation: Which drugs did the government get the best deals...
LARGO, MD — President Joe Biden and Vice President Kamala Harris rallied around the government’s release of the negotiated prices for the first 10 drugs impacted by a historic drug pricing law. But the...
View ArticleGenentech dissolves cancer immunology group, and research executive Ira...
Genentech is dismantling its cancer immunology team in a reorganization of its work in the field, and its VP of cancer immunology, Ira Mellman, will leave, the company confirmed to Endpoints News. The...
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Esperion's CMO hits the exit; Pfizer appoints Nvidia alum as AI chief
JoAnne Foody Esperion CMO JoAnne Foody has departed, the company disclosed in an Aug. 5 SEC filing. “We are grateful for her significant contributions to the company through the years and wish her the...
View ArticlePfizer, BioNTech review next steps as Covid and flu combo vaccine delivers...
In the Covid-19 and influenza combo vaccine race, Pfizer and BioNTech reported a hiccup on Friday with uneven results in a Phase 3 test. The companies’ Covid-flu vaccine didn’t meet the Phase 3 primary...
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Incyte plans label expansion for cancer drug Monjuvi following positive...
Incyte will go to the FDA by the end of the year with a supplemental BLA for its cancer drug Monjuvi after it hit all the endpoints in a Phase 3 study in follicular lymphoma. The Phase 3 inMIND trial...
View ArticleNovo Nordisk subsidiary to build $220M API facility for chronic disease drugs
Novo Nordisk Pharmatech is building a new facility in Denmark to expand capacity for raw material production due to “significantly higher demand” from its parent company. “This is the largest...
View ArticleAN2’s poison pill; Pfizer shares promising mid-stage data for flu shot
Plus, news about Vericel: AN2 Therapeutics adopts poison pill: The small molecule drugmaker put forth the stockholder rights plan for a year after one of its investors — BML Investment Partners —...
View ArticleQ&A: Lykos just cut 75% of its workforce after an FDA rejection. Here’s what...
In the span of a week, Lykos Therapeutics has been rejected by the FDA, had three published papers retracted, dealt with a boardroom shakeup and, yesterday, cut 75% of its roughly 100 employees. It’s a...
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Avantor sells off CRO for $650M to private equity firm
Audax Private Equity is buying Avantor’s CRO business for about $650 million. The deal, announced Friday, is for Avantor’s clinical services business, which includes kitting, biorepository and related...
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Carbon Health CEO Eren Bali steps down
(This story is from our new Health Tech newsletter. If you’d like to sign up, just click here.) Eren Bali has left his position as CEO of the urgent and primary care startup Carbon Health, the company...
View ArticleFDA approves AstraZeneca’s Imfinzi before and after lung cancer surgery
The FDA approved AstraZeneca’s checkpoint inhibitor Imfinzi for use in certain lung cancers before and after surgery, as the pharma company follows in the footsteps of Merck’s Keytruda. The approval...
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Medicare negotiations have concluded. What's next for court cases against the...
Multiple drugmakers say they are sticking with their legal strategies against the Inflation Reduction Act even though they agreed to negotiated prices for their therapies. The Centers for Medicare...
View ArticleUnpacking IRA price negotiations results; Lykos’ tough week; Genentech...
Welcome back to Endpoints Weekly, your review of the week’s top biopharma headlines. Want this in your inbox every Saturday morning? Current Endpoints readers can visit their reader profile to add...
View ArticleQ&A: Lilly’s top scientists on genetic medicine ambitions, and how they’re...
Last week, Eli Lilly opened the doors of its new research center in Boston, largely focused on genetic therapies. While the Indianapolis-based drugmaker’s $875 billion valuation largely stems from its...
View ArticleAvidity’s upsized $345M offering; Janus Henderson’s new $150M biotech fund
Plus, news about Phathom and CANbridge: Avidity Biosciences closes $345.1M offering: The raise comes on the heels of Phase 1/2 data earlier this month that showed its RNA drug candidate generated a 25%...
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