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Eyepoint sells $100M in shares after unveiling eye disease data for...

EyePoint Pharmaceuticals is selling $100 million worth of shares on the back of positive mid-stage data for a drug-device candidate in diabetic macular edema. The results pushed its share price up by...

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GSK buys autoimmune T cell engager for $300M upfront from Chimagen

As early data show how T cell engagers — originally developed for cancers — can potentially treat a range of autoimmune diseases, GSK is buying its own molecule from Chimagen Biosciences. The UK pharma...

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Two type 1 diabetes patients are insulin-free after Eledon's...

Eledon Pharmaceuticals’ experimental immunosuppressant helped two patients with type 1 diabetes go insulin-free following an islet cell transplant, the company announced Tuesday. The company's stock...

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Vera’s $300M offering; Abeona resubmits treatment for rare skin disease

Plus, news about Astellas, Clover, ElevateBio, Monopar, Idorsia and Neurocrine Biosciences: Vera Therapeutics plans $300M offering: The California biotech is selling shares after presenting Phase 2b...

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In bid to lower ARIA-E, Eli Lilly tries a different dosing regimen for its...

Eli Lilly presented new data illustrating how a different dosing regimen of its Alzheimer’s drug reduced the frequency of brain swelling. The results could help Lilly argue for a change to Kisunla’s...

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Novartis highlights overall M&A track record following MorphoSys impairment

Novartis CEO Vas Narasimhan assured investors on Tuesday that it takes a careful, systematic approach to M&A after recording an $800 million impairment to its recent MorphoSys acquisition. During...

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PacBio bets on 'inflection point' with $500 long-read genome

Pacific Biosciences says it can produce high-fidelity genetic code for as little as $500, a move that aims to reach more labs and revive the company's struggling business. The company on Tuesday...

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MilliporeSigma invests €70M to triple ADC manufacturing at US site 

Merck KGaA, through its life science arm MilliporeSigma, is again increasing its manufacturing footprint for ADCs, this time by allocating €70 million ($75.6 million) to expand production in North...

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Shionogi touts topline data for Covid-19 antiviral for post-exposure treatment

Shionogi’s once-daily 3CL protease inhibitor hit on a primary endpoint in a late-stage trial as a post-exposure prophylaxis treatment for Covid-19 after failing a Phase 3 study in May. The oral...

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Novartis expands Scemblix label to first-line CML patients

Novartis’ chronic myeloid leukemia drug Scemblix will now be available to newly diagnosed patients, the FDA announced on Tuesday. Scemblix was first approved in 2021 for use as a third-line treatment....

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Coya shares sink on Phase 2 Alzheimer's data for deprioritized drug

Coya Therapeutics’ stock price {$COYA} fell more than 20% on Tuesday after the company reported Phase 2 data for its Alzheimer’s disease program, called COYA 301. Though Coya de-emphasized COYA 301 as...

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FDA again questions Lexicon diabetes drug ahead of adcomm

The FDA is raising repeat safety and efficacy questions ahead of an advisory committee meeting on Thursday for Lexicon Pharmaceuticals' SGLT2 inhibitor sotagliflozin, which the agency rejected in 2019...

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What would RFK Jr. do on healthcare? Trump ally's FDA plans raise alarm

Donald Trump's embrace of Robert F. Kennedy Jr. is forcing biotech and pharma leaders to grapple with having US life sciences policy influenced by a figure who has extensively criticized vaccines and...

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Following March inspection, Novo Nordisk's semaglutide manufacturing facility...

The FDA on Tuesday released an inspection report sent to Novo Nordisk earlier this year citing quality-related issues at a site in Kalundborg, Denmark, that manufactures its blockbuster semaglutide...

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Pfizer shares new details on obesity pipeline, hints at ‘other opportunities’

As Pfizer talked up the strength of its pipeline Tuesday, it shared details for the first time about its plans in obesity and said it has a multi-pronged strategy to catch up to rivals in ...

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Zurzuvae won't be developed for major depression, Sage says

It’s official: Sage and Biogen will not attempt to get their postpartum depression pill Zurzuvae approved in the broader population of people with major depressive disorder. Sage, which has recently...

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Axonis snags $115M to test oral drugs for epilepsy and neuropathic pain

Boston biotech Axonis Therapeutics has raised a $115 million Series A to test whether its oral drug AXN-027 can help patients with focal epilepsy and diabetic neuropathic pain. The financing, disclosed...

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GSK remains ‘very confident’ in RSV vaccine amid competition, sales slump

Competition is heating up in the RSV space, despite a lukewarm quarter for vaccine uptake. Pfizer beat GSK’s Arexvy for the first time in the third quarter, as Arexvy sales dipped 72% from the year ...

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Nobel winner David Baker co-founds another startup, as Archon takes an AI...

The newest David Baker biotech startup launched Wednesday, as Archon Biosciences has raised a $20 million seed round to develop what it believes could be a new class of antibody-based drugs. The...

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Updated: Lilly’s shares tank after trimming revenue guidance. It also cut...

Eli Lilly lowered the top end of its full-year revenue guidance by $600 million on Wednesday, as its third-quarter sales were about $800 million below Wall Street’s expectations. The pharma giant had...

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